At LeoRios Lab, our research motivation focuses on promoting further understanding of the overlapping areas of Biochemical Engineering and Synthetic Biology, resulting in novel ways to apply this knowledge to tackle the global growing socio-economic inequalities. We have a firm belief that if scientists work together and gear their research and related activities towards this end, an immense contribution will be made fighting problems like equal access to food, energy and pharmaceuticals, boosting local bio-economies, access to high-quality education as well as the promotion of a sustainable environment.
Our research areas
Microbiol Cell Factories: Synthetic Biology and Metabolic Engineering
Engineering Microbial Consortia
Engineered Microbial Consortia In their natural habitat, microbial cells live in organised consortia reaching a steady state in terms of...
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CRISPR Based Low Cost Diagnostics
We are developing innovative approaches to leverage the power of CRISPR technology for rapid, affordable, and highly accurate diagnostic...
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Metabolic Engineering
Our group is working on applying synthetic biology tools to engineer microbial cell factories to produce high value a bulk products such as...
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Mammalian Cell Factories
Mammalian Cell Factories We are very excited to explore new production ways of biologics using mammalian cells. Therefore, we are venturing in...
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Multiplex Genome Engineering
By developing novel methods to simultaneously edit multiple genes or regulatory elements, we aim to accelerate the pace of research and unlock...
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Biocatalysis and Protein Engineering
We explore the vast potential of enzymes and other biocatalysts, working to optimize their function, stability, and specificity for a variety of...
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Integrated Bioprocessing
Synthetic biology has allowed the engineering of novel synthetic multi-enzymatic pathways to produce high value products in a sustainable way...
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Continuous Flow Bioprocessing
The bioprocessing industry has been mainly studied and commercialized using batch and fed-batch production methods, while little focus has been...
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Bioprocess Modelling using AI and Real-Time Monitoring
Our multi-disciplinary team employs different modelling approaches, including state-of-the-art AI algorithms and real-time monitoring technologies...
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Automation enhanced by Artificial Intelligence: Applications into Synthetic Biology
Our research group at UCL Biochemical Engineering is pioneering the convergence of artificial intelligence (AI) and automation within the realm of...
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Open-Source Automation in Synthetic Biology
Our research group at UCL Biochemical Engineering is deeply committed to democratizing synthetic biology through open-source automation. We are...
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High Throughput Microscale and Mini Bioreactors
Microscale Automated Bioprocessing Tools Microscale bioreators and its further automation have been a critical tool for the development of...
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We Develop Innovative Solutions
Metabolic Engineering and Systems Biology
Microbial Cell Factories for the Sustainable Production of Drugs, Biomaterials and Biofuels
- Anticancer Drug Taxol in S. cerevisiae
- Jet Biofuels in Yarrowia Lipolytica
- High Value Chiral Amino-alcohols in E. coli
- High Value Alkaloids (i.e Ephedrine) in S. cerevisiae
- Fragrances and Food Additives in E. coli and S. cerevisiae
High-throughput Bioreactors
Mini and Microscale Bioreactors to Speed Up Bioprocess Development Mimicking Large Scale Conditions
- Advanced Microplate Based Bioreactors
- Mini-Bioreactors Mimicking Industrial Scale Conditions
- Microscale Continuous Flow Bioreactors
- Low Cost 3D printed Bioreactors
- Microfluidic MicroBioreactors
Smart Biosensors and Diagnostics
Synthetic Biology Tools Applied for Low-Cost Diagnostics and Biosensing Capabilities
- CRISPR Based Diagnostics for COVID19
- Biosensors Applied in Aquaculture
- Digital Microfluidic Diagnostics
Automation and Artificial Intelligence
State of the Art Bio-Automation enhanced by Artificial Intelligence algorithms
- Open Source Low Cost Automation
- Edinburgh Genome BioFoundry
- Bio-Automation Enhanced Through Artificial Intelligence
- Automated Digital Microfluidics
Advanced Bioprocessing Technologies
Designing Novel Bioreactors and Intensified Bioprocesses to tackle Scale Up Challenges
- Integrated Bioprocessing
- Continuous Flow Bioprocesses
- Scale up of Mammalian Cells Systems
- Hybrid Biomodelling combining Machine Learning and deterministic algorithms
- Life Cycle Assessments
from the blog
Learn About Our Latest Developments and News
Digital Microfluidics Workship
About the Biomedical Automation Network: The Biomedical Lab Automation (BLA) network aims to coordinate and maximize the potential of the University’s automation...
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Standardization of biological parts for S. cerevisiae: a BioRoboost newsletter
As our understanding of genetic circuits has improved, there has been a shift towards standardisation of the design process. This entails the creation of a library of...
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