Publications
2024
- E. Shire, A. Coimbra, C. Ostria, L. Rios‐Solis, D. Barreiro. Molecular design of protein-based materials – state of the art, opportunities and challenges at the interface between materials engineering and synthetic biology. 2024. Molecular Systems Design & Engineering.
- S. Pannerchelvan, L. Rios-Solis, H. Wasoh, M. Sobri, F. Wong, M. Mohamed, R. Mohamad, M. Halim. Functional yogurt: a comprehensive review of its nutritional composition and health benefits. 2024. Food Function. 15 (10927-10955)
- G. Galindo-Rodriguez, M. Sarwar, L. Rios-Solis, S. Dimartino. Development, characterization and application of 3D printed adsorbents for in situ recovery of taxadiene from microbial cultivations. 2024. Journal of Chromatography. 1721 (464815)
- B. Nowrouzi, P. Torres-Montero, E. Kerkhoven, J. Martinez, L. Rios-Solis. Rewiring Saccharomyces cerevisiae metabolism for optimised Taxol® precursors production. 2024. Metabolic Engineering Communications. 18 (e00229)
- G. Sodhi, G. Kaur, N. George, H. Walia, D. Sillu, S. Rath, S. Saxena, L. Rios-Solis, V. Dwibedi. Waste to wealth: microbial-based valorization of grape pomace for nutraceutical, cosmetic, and therapeutic applications to promote circular economy. 2024. Process Safety and Environmental Protection. 188 (1464 – 1478)
- A. Escrich, N. Jonguitud-Borrego, K. Malci, R. Sanchez-Muroz, J. Palazon, L. Rios-Solis, E. Mayano. A novel step towards the heterologous biosynthesis of paclitaxel: Characterization of T1βOH taxane hydroxylase. 2024. Metabolic Engineering. 85 (201-212)
- V. Hernandez-Maldonado, A. Erdely, M. Diaz-Viera, L. Rios-Solis. Fast procedure to compute empirical and Bernstein copulas. 2024. Applied Mathematics and Computation. 477 (e00229)
- A. Constantinous, S. Hafeez, E. Harkou, P. Adamou, E. Pallari, G. Manos, A. Webb, R. Kotha, O. Morgen, L. Walls, L. Rios-Solis, R. Dewil, S. Al-Salem. Fuel Quality from Thermochemical Conversion and Biological Treatment of Biomass. 2024. ACS Publications. 63,44 (18699 – 18723)
2023
- JH Santoyo‐Garcia, L. E Walls, M. Valdivia‐Cabrera, K. Malcı, N. Jonguitud‐Borrego, K. J Halliday, L. Rios‐Solis. The synergetic effect from the combination of different adsorption resins in batch and semi-continuous cultivations of S. cerevisiaecell factories to produce acetylated Taxanes precursors of the anticancer drug Taxol. 2023. Biotechnology and Bioengineering. 20 (2160-2174)
- J Vicencio-Medina, Y. A Rios-Solis, O. J. Ibarra-Rojas, N. M Cid-Garcia, L. Rios-Solis. The maximal covering location problem with accessibility indicators and mobile units. 2023. Socio-Economic Planning Sciences. 87 (101597)
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. R. Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2023. Critical Reviews in Biotechnology. (4) 594-612
- R Galindo-Rodriguez, J. H Santoyo-Garcia, L. Rios-Solis, S. Dimartino. In situ recovery of taxadiene using solid adsorption in cultivations with Saccharomyces cerevisiae. 2023. Preparative Biochemistry & Biotechnology. 1(9)
- Ripoll, J. Alexis Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis, L. Betancor. New perspectives into Gluconobacter-catalysed biotransformations. 2023. Biotechnology Advances 65 (108127)
- Imanina Abdullah Thaidi, R. Mohamad, H. Wasoh, M. Rizal Kapri, A. Badruddin Ghazali, J. Shun Tan, L. Rios-Solis, M. Halim. Development of In Situ Product Recovery (ISPR) System Using Amberlite IRA67 for Enhanced Biosynthesis of Hyaluronic Acid by Streptococcus zooepidemicus 2023. Life. 13-558
- Kerem Kalkan, F. Palaz, S. Sofija, N. Elmousa, Y. Ledezma, E. Cachat, L. Rios-Solis. Improving recombinant protein production in CHO cells using the CRISPR-Cas system. 2023. Biotechnology Advances. 64 (108115)
- Pannerchelvan, L. Rios-Solis, F. Wong Faizal Wong, U. Hasanah Zaidan, H. Wasoh, M. Shamzi Mohamed, J. Shun Tan, R. Mohamad, M. Halim. Strategies for improvement of gamma-aminobutyric acid (GABA) biosynthesis via lactic acid bacteria (LAB) fermentation. 2023. Food Funct , Advance Article
- Dwibedi, S. Kumar Rath, S. Jain, N. Martínez-Argueta, R. Prakash, S. Saxena, L. Rios-Solis. Key insights into secondary metabolites from various Chaetomium species. 2023, Applied Microbiology and Biotechnology. 107, 1077–1093
- M. El-Sharoud, S. A Zalma, L. Rios-Solis, R. Ledesma-Amaro. Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox. 2023. Biotechnology Notes. 4, 14-19
- E. Walls, P. Otoupal, R. Ledesma-Amaro, S. B. Velasquez-Orta, J. M. Gladden, L. Rios-Solis. Bioconversion of cellulose into isoprenoid bio-jet fuel candidates using rumen bacteria and non-conventional yeast. 2023. Bioresources and Biotechnology. 368, 128216
2022
- Malci. N. Jonguitud-Borrego, H. van der Straten Waillet, U. Puodžiu̅naitė, E. J. Johnston, S. J. Rosser, and L. Rios-Solis. ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time. 2022. ACS synthetic biology. 11, 3629–3643
- Nowrouzi, L. Lungang, L. Rios-Solis. Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae. 2022. Microbial Cell Factories. 21(1), 1-24
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2022. Critical Reviews in Biotechnology, 1-19
- J. Torres-Sebastian, J. G. Colli-Mull, L. Escobedo-Sanchez, D. Martinez-Fong, L. Rios-Solis, M. E Gutierrez-Castillo, G. López-Jiménez, M. L Moreno-Rivera, L. R Tovar-Galvez, A. J Espadas-Alvarez. Methane, a renewable biofuel: from organic waste to bioenergy. 2022. Biofuels. 13 (7) 907-917
- Malcl, E. Watts, T. Michelle Roberts, J. Yam Auxillos, B. Nowrouzi, H. Oss Boll, C. Nascimento, A. Andreou, P. Vegh, S. Donovan, R. Fragkoudis, S. Panke, E. Wallace, A. Elfick, L. Rios-Solis. Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiaeand Emerging Yeast Species. 2022. ACS synthetic biology. 11, 527-547
- Malci, L. E. Walls and L Rios-Solis. Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments. 2022. ACS Synthetic Biology, 11, 4, 1555–1567
- Jonguitud-Borrego, K. Malcı, M. Anand, E. Baluku, C. Webb, L. Liang, C. Barba-Ostria, L. P Guaman, L. Hui, L. Rios-Solis. High—throughput and automated screening for COVID-19. 2022. Frontiers in Medical Technology. (4)
- H. Santoyo-Garcia, L. E. Walls, B. Nowrouzi, G.R Galindo-Rodriguez, M. Ochoa-Villareal, G. J. Loake, S. Dimartino, L.Rios-Solis. In situ solid-liquid extraction enhances recovery of taxadiene from engineered S. cerevisiae cell factories. 2022. Journal of Separation and Purification Sciences, 290, 120880
- Thangsunan, S. Temisak, T. Jaimalai, L Rios-Solis, N Suree. Sensitive Detection of Chicken Meat in Commercial Processed Food Products Based on One-Step Colourimetric Loop-Mediated Isothermal Amplification. 2022. Food Analytical Methods, 1-15
- E Walls, J.L Martinez, E.A del Rio Chanona, L Rios‐Solis. Definitive screening accelerates Taxol biosynthetic pathway optimization and scale up in Saccharomyces cerevisiaecell factories 2022. Biotechnology Journal, 17 (1), 210041
- E. Walls, J. L. Martinez, L. Rios-Solis. Enhancing Saccharomyces cerevisiaeTaxane Biosynthesis and Overcoming Nutritional Stress-Induced Pseudohyphal Growth. 2022. Microorganisms.10(1):163
2021
- P. Guaman-Bautista, E. Moreta U, C. G. O.-Arias, M. Torres-Arias, N. C. Kyriakidis, K. Malcı, N.Jonguitud-Borrego, L. Rios-Solis, E. Ramos-Martinez, A. López-Cortés, C. Barba-Ostria. Tracking SARS-Cov-2: Novel Trends and Diagnostics Strategies. 2021. Journal of Diagnostics . 11, 1981.
- Morris, R. Gacia Arrazola, L. Rios-Solis and P. A. Dalby. Biophysical characterization of E.Coli transketolase by aqueous cosolvents. 2021.Nature Scientific Report .11,1, 1-16.
- Teworte, K. Malcı, L. E. Walls, M. Halim, L. Rios-Solis Recent advances in fed-batch microscale bioreactor design. 2021. Biotechnology Advances. 107888
- Temisak, J. Boonil, W. Yenchum, K. Hongthong, T. yat, L. Rios-Solis and P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration 2021. International Journal of Food Science and Technology. 56,12, 6345-6358
- Nowrouzi, L. Rios-Solis. Redox metabolism for improving whole-cell P450-catalysed terpenoid biosynthesis 8 november 2021. Critical Reviews in Biotechnology. 1-25
- Muhammad Fakhri Zainuddin, Chong Kar Fai, Arbakariya B Ariff, Leonardo Rios-Solis, Murni Halim. Current Pretreatment/Cell Disruption and Extraction Methods Used to Improve Intracellular Lipid Recovery from Oleaginous Yeasts. 2021. Microorganisms 9(2), 251
2020
L. Walls, K. Malci, B. Nowrouzi, R. Li, L. d’Espaux, J. Wong, J. Dennis, A. Semiao, S. Wallace, J. Martinez, J. D. Keasling, L. Rios-Solis. Optimising the biosynthesis of oxygenated and acetylated Taxol precursors in S. cerevisiae using advanced bioprocessing strategies. Biotech BioEng J. 2020. https://doi.org/10.1002/bit.27569
B. Nowrouzi, R. Li, L. E. Walls, L. d’Espaux, K. Malci, L. Liang, N. Jonguitud Borrego, A. I. Lerma Escalera, J. R. Morones-Ramirez, J. D. Keasling, L. Rios Solis. Enhanced production of taxadiene in S. cerevisiae. Manuscript accepted for publication at Microb. Cell Fac. 2020. doi.org/10.1101/2020.06.08.13960
K. Malci, L E. Walls. L. Rios-Solis. Multiplex Genome Engineering Methods for Yeast Cell Factory Development. Epub ahead of publication. Front. Bioeng. Biotechnol. 2020. doi: 10.3389/fbioe.2020.589468
P. Morris, R. Garcia Arrazola, L. Rios-Solis, Paul A Dalby. Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents. BioRxiv. 2020. doi.org/10.1101/2020.06.09.140988
P. Thangsunan, S. Temisak, P. Morris, L. Rios-Solis, N. Suree. Combination of loop-mediated isothermal amplification and AuNP-oligoprobe colourimetric assay for pork authentication in processed-meat products. Paper accepted for publication at J. Food Anal. Methods. 2020. doi.org/10.1101/2020.07.12.199091
S. Temisak, P. Thangsunan, J. Boonil, W. Yenchum, K. Hongthong, T. Yata, L. Rios-Solis, P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration. BioRxiv 2020. doi.org/10.1101/2020.06.14.150375
L. E. Walls, L. Rios-Solis. Sustainable microbial isoprenoid derived advanced biojet fuel production: a review. J. Biotech. Bioeng. Epub ahead of publication. 2020. doi:10.3389/fbioe.2020.599560
J. Beal, A. Go.i‐Moreno, C. Myers, A. Hecht, M. del Carmen de Vicente, M. Parco, M. Schmidt, K. Timmis, G. Baldwin, S. Friedrichs, P. Freemont, D. Kiga, E. Ordozgoiti, M. Rennig, L. Rios Solis, K. Tanner, V. de Lorenzo, M. Porcar. The long journey towards standards for engineering biosystems. EMBO Rep. 2020. 6; 21(5). doi.org/10.15252/embr.202050521
2018
P. Wilk, H. Murni, L. Rios-Solis. 2018. Recent Advances and Impacts of Microtiter Plate-Based Fermentations in Synthetic Biology and Bioprocess Development. Fermentation Microbiology and Biotechnology, 4th edition. Taylor and Francis Publishers. 18:359-372
N.F Fazilah, A.B Ariff, M.E Khayat, L. Rios-Solis, M Halim. 2018. Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt. J. Funct. Foods 48, 387-399. doi.org/10.1016/j.jff.2018.07.039
M. Othman, A. B. Ariff, M. R. Kapri, L. Rios-Solis, M. Halim. 2018. Growth enhancement of probiotic Pediococcus acidilactici by extractive fermentation of lactic acid exploiting anion-exchange resin. Fronts. Microbiol. 9, 2554. doi.org/10.3389/fmicb.2018.02554
J. Wong, T. de Rond, L. d’Espaux, C. V. Horst, I. Dev, L. Rios-Solis, J. Kirby, H. Scheller, Jay Keasling. 2018. High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae. Metab. Eng. 45:142-148. doi.org/10.1016/j.ymben.2017.12.007
2017
M. Othman, A. B. Ariff, L. Rios-Solis, M. Halim. 2017. Extractive Fermentation of Lactic Acid in Lactic Acid Bacteria Cultivation: A Review. Fronts. Microbiol. 8: 2285 doi.org/10.3389/fmicb.2017.02285
J. Wong, L. Rios-Solis, J. D. Keasling. Microbial production of isoprenoids. 2017. Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals. Part of the series Handbook of Hydrocarbon and Lipid Microbiology Springer, Berlin, Germany pp. 21-24.
K. Markošov., I. Dolejš, R. Stloukal, L. Rios-Solis, M. Rosenberg, M. Micheletti, G. J. Lye, N. J. Turner, M. Rebroš. 2016. Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels. J. Mol. Cat. B. Enz. 129:69-74. doi.org/10.1016/j.molcatb.2016.04.009
2016
P. Morris, L. Rios-Solis, R. Garc.a-Arrazola, G. J. Lye and P. A. Dalby. 2016. Impact of cofactorbinding loop mutations on thermotolerance and activity of E. coli transketolase. Enz Microb Tech. 89:85-91. DOI: 10.1016/j.enzmictec.2016.04.003
L. Rios-Solis, P. Morris, H. Al-Bahrani, C. Du. Immobilized biospheres filtration system using unidirectional flow. U.K. Patent Application GB1602673.4, filed 16 February 2016. Patent Pending.
2015
L. Rios-Solis, B. Mothia, S. Yi, Z.Yuhong, M. Micheletti and G. J. Lye. 2015. High throughout monoamine oxidase (MAO-N) screening and kinetic model generation. J. Mol. Cat. B. Enz. 120-100-110. doi.org/10.1016/j.molcatb.2015.07.001
L. Rios-Solis, P. Morris, A. Odeleye, C. Grant, J.M. Ward, P.A. Dalby, F. Baganz and G.J. Lye. 2015. Modelling and optimization of the one-pot synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. Chem. Eng Sci. 122: 360–372. DOI:10.1016/J.CES.2014.09.046
2014
C.J. Du, L. Rios-Solis, J.M. Ward, P. A. Dalby, G. J. Lye. 2014. Evaluation of the CV2025 ω-transaminase for the bioconversion of lignin breakdown products into value-added chemicals. Biocat. Biotrans. 32:302-313. doi.org/10.3109/10242422.2014.976632
M. Halim, L. Rios-Solis. M. Micheletti, J. M. Ward and G.J. Lye. 2014. Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines. Bioprocess Biosyst. Eng. 37:931-41. DOI: 10.1007/s00449-013-1065-5
2013
L. Rios-Solis, N. Bayir, M. Halim., J. Hao, F. Baganz., G.J. Lye. 2013. Non-linear kinetic modelling of reversible bioconversions: application to the transaminase catalysed synthesis of chiral amino-alcohols. Biochem. Eng. J. 73:38-48. doi.org/10.1016/j.bej.2013.01.010
2011
L. Rios-Solis, M. Halim, A. C.zares, P. Morris, J. M. Ward, H.C. Hailes, P.A. Dalby, F. Baganz and G.J. Lye. 2011. A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’ E. coli expression system with microscale experimentation. Biocat. Biotrans. 29: 192-203. doi.org/10.3109/10242422.2011.609589
2010
A. C.zares, J. L. Galman, L. G. Crago, M. E. B. Smith, J. Strafford, L. Rios-Solis, G. J. Lye, P. A. Dalby and H. C. Hailes. 2010. Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes. Org. Biomol. Chem. 8: 1301–1309. DOI: 10.1039/b924144b
2009
F. Baganz, S. Matosevic, L. Rios, G. Lye, A. Jadhav, N. Szita. 2009. Towards engineering of de novo pathways for the synthesis of chiral chemicals using in vitro and in vivo approaches. New Biotechnol. 25: 159-160. 10.1016/j.nbt.2009.06.511
2023
- JH Santoyo‐Garcia, L. E Walls, M. Valdivia‐Cabrera, K. Malcı, N. Jonguitud‐Borrego, K. J Halliday, L. Rios‐Solis. The synergetic effect from the combination of different adsorption resins in batch and semi-continuous cultivations of S. cerevisiaecell factories to produce acetylated Taxanes precursors of the anticancer drug Taxol. 2023. Biotechnology and Bioengineering. 20 (2160-2174)
- J Vicencio-Medina, Y. A Rios-Solis, O. J. Ibarra-Rojas, N. M Cid-Garcia, L. Rios-Solis. The maximal covering location problem with accessibility indicators and mobile units. 2023. Socio-Economic Planning Sciences. 87 (101597)
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. R. Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2023. Critical Reviews in Biotechnology. (4) 594-612
- R Galindo-Rodriguez, J. H Santoyo-Garcia, L. Rios-Solis, S. Dimartino. In situ recovery of taxadiene using solid adsorption in cultivations with Saccharomyces cerevisiae. 2023. Preparative Biochemistry & Biotechnology. 1(9)
- Ripoll, J. Alexis Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis, L. Betancor. New perspectives into Gluconobacter-catalysed biotransformations. 2023. Biotechnology Advances 65 (108127)
- Imanina Abdullah Thaidi, R. Mohamad, H. Wasoh, M. Rizal Kapri, A. Badruddin Ghazali, J. Shun Tan, L. Rios-Solis, M. Halim. Development of In Situ Product Recovery (ISPR) System Using Amberlite IRA67 for Enhanced Biosynthesis of Hyaluronic Acid by Streptococcus zooepidemicus 2023. Life. 13-558
- Kerem Kalkan, F. Palaz, S. Sofija, N. Elmousa, Y. Ledezma, E. Cachat, L. Rios-Solis. Improving recombinant protein production in CHO cells using the CRISPR-Cas system. 2023. Biotechnology Advances. 64 (108115)
- Pannerchelvan, L. Rios-Solis, F. Wong Faizal Wong, U. Hasanah Zaidan, H. Wasoh, M. Shamzi Mohamed, J. Shun Tan, R. Mohamad, M. Halim. Strategies for improvement of gamma-aminobutyric acid (GABA) biosynthesis via lactic acid bacteria (LAB) fermentation. 2023. Food Funct , Advance Article
- Dwibedi, S. Kumar Rath, S. Jain, N. Martínez-Argueta, R. Prakash, S. Saxena, L. Rios-Solis. Key insights into secondary metabolites from various Chaetomium species. 2023, Applied Microbiology and Biotechnology. 107, 1077–1093
- M. El-Sharoud, S. A Zalma, L. Rios-Solis, R. Ledesma-Amaro. Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox. 2023. Biotechnology Notes. 4, 14-19
- E. Walls, P. Otoupal, R. Ledesma-Amaro, S. B. Velasquez-Orta, J. M. Gladden, L. Rios-Solis. Bioconversion of cellulose into isoprenoid bio-jet fuel candidates using rumen bacteria and non-conventional yeast. 2023. Bioresources and Biotechnology. 368, 128216
2022
- Malci. N. Jonguitud-Borrego, H. van der Straten Waillet, U. Puodžiu̅naitė, E. J. Johnston, S. J. Rosser, and L. Rios-Solis. ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time. 2022. ACS synthetic biology. 11, 3629–3643
- Nowrouzi, L. Lungang, L. Rios-Solis. Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae. 2022. Microbial Cell Factories. 21(1), 1-24
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2022. Critical Reviews in Biotechnology, 1-19
- J. Torres-Sebastian, J. G. Colli-Mull, L. Escobedo-Sanchez, D. Martinez-Fong, L. Rios-Solis, M. E Gutierrez-Castillo, G. López-Jiménez, M. L Moreno-Rivera, L. R Tovar-Galvez, A. J Espadas-Alvarez. Methane, a renewable biofuel: from organic waste to bioenergy. 2022. Biofuels. 13 (7) 907-917
- Malcl, E. Watts, T. Michelle Roberts, J. Yam Auxillos, B. Nowrouzi, H. Oss Boll, C. Nascimento, A. Andreou, P. Vegh, S. Donovan, R. Fragkoudis, S. Panke, E. Wallace, A. Elfick, L. Rios-Solis. Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiaeand Emerging Yeast Species. 2022. ACS synthetic biology. 11, 527-547
- Malci, L. E. Walls and L Rios-Solis. Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments. 2022. ACS Synthetic Biology, 11, 4, 1555–1567
- Jonguitud-Borrego, K. Malcı, M. Anand, E. Baluku, C. Webb, L. Liang, C. Barba-Ostria, L. P Guaman, L. Hui, L. Rios-Solis. High—throughput and automated screening for COVID-19. 2022. Frontiers in Medical Technology. (4)
- H. Santoyo-Garcia, L. E. Walls, B. Nowrouzi, G.R Galindo-Rodriguez, M. Ochoa-Villareal, G. J. Loake, S. Dimartino, L.Rios-Solis. In situ solid-liquid extraction enhances recovery of taxadiene from engineered S. cerevisiae cell factories. 2022. Journal of Separation and Purification Sciences, 290, 120880
- Thangsunan, S. Temisak, T. Jaimalai, L Rios-Solis, N Suree. Sensitive Detection of Chicken Meat in Commercial Processed Food Products Based on One-Step Colourimetric Loop-Mediated Isothermal Amplification. 2022. Food Analytical Methods, 1-15
- E Walls, J.L Martinez, E.A del Rio Chanona, L Rios‐Solis. Definitive screening accelerates Taxol biosynthetic pathway optimization and scale up in Saccharomyces cerevisiaecell factories 2022. Biotechnology Journal, 17 (1), 210041
- E. Walls, J. L. Martinez, L. Rios-Solis. Enhancing Saccharomyces cerevisiaeTaxane Biosynthesis and Overcoming Nutritional Stress-Induced Pseudohyphal Growth. 2022. Microorganisms.10(1):163
2021
- P. Guaman-Bautista, E. Moreta U, C. G. O.-Arias, M. Torres-Arias, N. C. Kyriakidis, K. Malcı, N.Jonguitud-Borrego, L. Rios-Solis, E. Ramos-Martinez, A. López-Cortés, C. Barba-Ostria. Tracking SARS-Cov-2: Novel Trends and Diagnostics Strategies. 2021. Journal of Diagnostics . 11, 1981.
- Morris, R. Gacia Arrazola, L. Rios-Solis and P. A. Dalby. Biophysical characterization of E.Coli transketolase by aqueous cosolvents. 2021.Nature Scientific Report .11,1, 1-16.
- Teworte, K. Malcı, L. E. Walls, M. Halim, L. Rios-Solis Recent advances in fed-batch microscale bioreactor design. 2021. Biotechnology Advances. 107888
- Temisak, J. Boonil, W. Yenchum, K. Hongthong, T. yat, L. Rios-Solis and P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration 2021. International Journal of Food Science and Technology. 56,12, 6345-6358
- Nowrouzi, L. Rios-Solis. Redox metabolism for improving whole-cell P450-catalysed terpenoid biosynthesis 8 november 2021. Critical Reviews in Biotechnology. 1-25
- Muhammad Fakhri Zainuddin, Chong Kar Fai, Arbakariya B Ariff, Leonardo Rios-Solis, Murni Halim. Current Pretreatment/Cell Disruption and Extraction Methods Used to Improve Intracellular Lipid Recovery from Oleaginous Yeasts. 2021. Microorganisms 9(2), 251
2020
L. Walls, K. Malci, B. Nowrouzi, R. Li, L. d’Espaux, J. Wong, J. Dennis, A. Semiao, S. Wallace, J. Martinez, J. D. Keasling, L. Rios-Solis. Optimising the biosynthesis of oxygenated and acetylated Taxol precursors in S. cerevisiae using advanced bioprocessing strategies. Biotech BioEng J. 2020. https://doi.org/10.1002/bit.27569
B. Nowrouzi, R. Li, L. E. Walls, L. d’Espaux, K. Malci, L. Liang, N. Jonguitud Borrego, A. I. Lerma Escalera, J. R. Morones-Ramirez, J. D. Keasling, L. Rios Solis. Enhanced production of taxadiene in S. cerevisiae. Manuscript accepted for publication at Microb. Cell Fac. 2020. doi.org/10.1101/2020.06.08.13960
K. Malci, L E. Walls. L. Rios-Solis. Multiplex Genome Engineering Methods for Yeast Cell Factory Development. Epub ahead of publication. Front. Bioeng. Biotechnol. 2020. doi: 10.3389/fbioe.2020.589468
P. Morris, R. Garcia Arrazola, L. Rios-Solis, Paul A Dalby. Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents. BioRxiv. 2020. doi.org/10.1101/2020.06.09.140988
P. Thangsunan, S. Temisak, P. Morris, L. Rios-Solis, N. Suree. Combination of loop-mediated isothermal amplification and AuNP-oligoprobe colourimetric assay for pork authentication in processed-meat products. Paper accepted for publication at J. Food Anal. Methods. 2020. doi.org/10.1101/2020.07.12.199091
S. Temisak, P. Thangsunan, J. Boonil, W. Yenchum, K. Hongthong, T. Yata, L. Rios-Solis, P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration. BioRxiv 2020. doi.org/10.1101/2020.06.14.150375
L. E. Walls, L. Rios-Solis. Sustainable microbial isoprenoid derived advanced biojet fuel production: a review. J. Biotech. Bioeng. Epub ahead of publication. 2020. doi:10.3389/fbioe.2020.599560
J. Beal, A. Go.i‐Moreno, C. Myers, A. Hecht, M. del Carmen de Vicente, M. Parco, M. Schmidt, K. Timmis, G. Baldwin, S. Friedrichs, P. Freemont, D. Kiga, E. Ordozgoiti, M. Rennig, L. Rios Solis, K. Tanner, V. de Lorenzo, M. Porcar. The long journey towards standards for engineering biosystems. EMBO Rep. 2020. 6; 21(5). doi.org/10.15252/embr.202050521
2018
P. Wilk, H. Murni, L. Rios-Solis. 2018. Recent Advances and Impacts of Microtiter Plate-Based Fermentations in Synthetic Biology and Bioprocess Development. Fermentation Microbiology and Biotechnology, 4th edition. Taylor and Francis Publishers. 18:359-372
N.F Fazilah, A.B Ariff, M.E Khayat, L. Rios-Solis, M Halim. 2018. Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt. J. Funct. Foods 48, 387-399. doi.org/10.1016/j.jff.2018.07.039
M. Othman, A. B. Ariff, M. R. Kapri, L. Rios-Solis, M. Halim. 2018. Growth enhancement of probiotic Pediococcus acidilactici by extractive fermentation of lactic acid exploiting anion-exchange resin. Fronts. Microbiol. 9, 2554. doi.org/10.3389/fmicb.2018.02554
J. Wong, T. de Rond, L. d’Espaux, C. V. Horst, I. Dev, L. Rios-Solis, J. Kirby, H. Scheller, Jay Keasling. 2018. High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae. Metab. Eng. 45:142-148. doi.org/10.1016/j.ymben.2017.12.007
2017
M. Othman, A. B. Ariff, L. Rios-Solis, M. Halim. 2017. Extractive Fermentation of Lactic Acid in Lactic Acid Bacteria Cultivation: A Review. Fronts. Microbiol. 8: 2285 doi.org/10.3389/fmicb.2017.02285
J. Wong, L. Rios-Solis, J. D. Keasling. Microbial production of isoprenoids. 2017. Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals. Part of the series Handbook of Hydrocarbon and Lipid Microbiology Springer, Berlin, Germany pp. 21-24.
K. Markošov., I. Dolejš, R. Stloukal, L. Rios-Solis, M. Rosenberg, M. Micheletti, G. J. Lye, N. J. Turner, M. Rebroš. 2016. Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels. J. Mol. Cat. B. Enz. 129:69-74. doi.org/10.1016/j.molcatb.2016.04.009
2016
P. Morris, L. Rios-Solis, R. Garc.a-Arrazola, G. J. Lye and P. A. Dalby. 2016. Impact of cofactorbinding loop mutations on thermotolerance and activity of E. coli transketolase. Enz Microb Tech. 89:85-91. DOI: 10.1016/j.enzmictec.2016.04.003
L. Rios-Solis, P. Morris, H. Al-Bahrani, C. Du. Immobilized biospheres filtration system using unidirectional flow. U.K. Patent Application GB1602673.4, filed 16 February 2016. Patent Pending.
2015
L. Rios-Solis, B. Mothia, S. Yi, Z.Yuhong, M. Micheletti and G. J. Lye. 2015. High throughout monoamine oxidase (MAO-N) screening and kinetic model generation. J. Mol. Cat. B. Enz. 120-100-110. doi.org/10.1016/j.molcatb.2015.07.001
L. Rios-Solis, P. Morris, A. Odeleye, C. Grant, J.M. Ward, P.A. Dalby, F. Baganz and G.J. Lye. 2015. Modelling and optimization of the one-pot synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. Chem. Eng Sci. 122: 360–372. DOI:10.1016/J.CES.2014.09.046
2014
C.J. Du, L. Rios-Solis, J.M. Ward, P. A. Dalby, G. J. Lye. 2014. Evaluation of the CV2025 ω-transaminase for the bioconversion of lignin breakdown products into value-added chemicals. Biocat. Biotrans. 32:302-313. doi.org/10.3109/10242422.2014.976632
M. Halim, L. Rios-Solis. M. Micheletti, J. M. Ward and G.J. Lye. 2014. Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines. Bioprocess Biosyst. Eng. 37:931-41. DOI: 10.1007/s00449-013-1065-5
2013
L. Rios-Solis, N. Bayir, M. Halim., J. Hao, F. Baganz., G.J. Lye. 2013. Non-linear kinetic modelling of reversible bioconversions: application to the transaminase catalysed synthesis of chiral amino-alcohols. Biochem. Eng. J. 73:38-48. doi.org/10.1016/j.bej.2013.01.010
2011
L. Rios-Solis, M. Halim, A. C.zares, P. Morris, J. M. Ward, H.C. Hailes, P.A. Dalby, F. Baganz and G.J. Lye. 2011. A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’ E. coli expression system with microscale experimentation. Biocat. Biotrans. 29: 192-203. doi.org/10.3109/10242422.2011.609589
2010
A. C.zares, J. L. Galman, L. G. Crago, M. E. B. Smith, J. Strafford, L. Rios-Solis, G. J. Lye, P. A. Dalby and H. C. Hailes. 2010. Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes. Org. Biomol. Chem. 8: 1301–1309. DOI: 10.1039/b924144b
2009
F. Baganz, S. Matosevic, L. Rios, G. Lye, A. Jadhav, N. Szita. 2009. Towards engineering of de novo pathways for the synthesis of chiral chemicals using in vitro and in vivo approaches. New Biotechnol. 25: 159-160. 10.1016/j.nbt.2009.06.511
2023
- JH Santoyo‐Garcia, L. E Walls, M. Valdivia‐Cabrera, K. Malcı, N. Jonguitud‐Borrego, K. J Halliday, L. Rios‐Solis. The synergetic effect from the combination of different adsorption resins in batch and semi-continuous cultivations of S. cerevisiaecell factories to produce acetylated Taxanes precursors of the anticancer drug Taxol. 2023. Biotechnology and Bioengineering. 20 (2160-2174)
- J Vicencio-Medina, Y. A Rios-Solis, O. J. Ibarra-Rojas, N. M Cid-Garcia, L. Rios-Solis. The maximal covering location problem with accessibility indicators and mobile units. 2023. Socio-Economic Planning Sciences. 87 (101597)
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. R. Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2023. Critical Reviews in Biotechnology. (4) 594-612
- R Galindo-Rodriguez, J. H Santoyo-Garcia, L. Rios-Solis, S. Dimartino. In situ recovery of taxadiene using solid adsorption in cultivations with Saccharomyces cerevisiae. 2023. Preparative Biochemistry & Biotechnology. 1(9)
- Ripoll, J. Alexis Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis, L. Betancor. New perspectives into Gluconobacter-catalysed biotransformations. 2023. Biotechnology Advances 65 (108127)
- Imanina Abdullah Thaidi, R. Mohamad, H. Wasoh, M. Rizal Kapri, A. Badruddin Ghazali, J. Shun Tan, L. Rios-Solis, M. Halim. Development of In Situ Product Recovery (ISPR) System Using Amberlite IRA67 for Enhanced Biosynthesis of Hyaluronic Acid by Streptococcus zooepidemicus 2023. Life. 13-558
- Kerem Kalkan, F. Palaz, S. Sofija, N. Elmousa, Y. Ledezma, E. Cachat, L. Rios-Solis. Improving recombinant protein production in CHO cells using the CRISPR-Cas system. 2023. Biotechnology Advances. 64 (108115)
- Pannerchelvan, L. Rios-Solis, F. Wong Faizal Wong, U. Hasanah Zaidan, H. Wasoh, M. Shamzi Mohamed, J. Shun Tan, R. Mohamad, M. Halim. Strategies for improvement of gamma-aminobutyric acid (GABA) biosynthesis via lactic acid bacteria (LAB) fermentation. 2023. Food Funct , Advance Article
- Dwibedi, S. Kumar Rath, S. Jain, N. Martínez-Argueta, R. Prakash, S. Saxena, L. Rios-Solis. Key insights into secondary metabolites from various Chaetomium species. 2023, Applied Microbiology and Biotechnology. 107, 1077–1093
- M. El-Sharoud, S. A Zalma, L. Rios-Solis, R. Ledesma-Amaro. Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox. 2023. Biotechnology Notes. 4, 14-19
- E. Walls, P. Otoupal, R. Ledesma-Amaro, S. B. Velasquez-Orta, J. M. Gladden, L. Rios-Solis. Bioconversion of cellulose into isoprenoid bio-jet fuel candidates using rumen bacteria and non-conventional yeast. 2023. Bioresources and Biotechnology. 368, 128216
2022
- Malci. N. Jonguitud-Borrego, H. van der Straten Waillet, U. Puodžiu̅naitė, E. J. Johnston, S. J. Rosser, and L. Rios-Solis. ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time. 2022. ACS synthetic biology. 11, 3629–3643
- Nowrouzi, L. Lungang, L. Rios-Solis. Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae. 2022. Microbial Cell Factories. 21(1), 1-24
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2022. Critical Reviews in Biotechnology, 1-19
- J. Torres-Sebastian, J. G. Colli-Mull, L. Escobedo-Sanchez, D. Martinez-Fong, L. Rios-Solis, M. E Gutierrez-Castillo, G. López-Jiménez, M. L Moreno-Rivera, L. R Tovar-Galvez, A. J Espadas-Alvarez. Methane, a renewable biofuel: from organic waste to bioenergy. 2022. Biofuels. 13 (7) 907-917
- Malcl, E. Watts, T. Michelle Roberts, J. Yam Auxillos, B. Nowrouzi, H. Oss Boll, C. Nascimento, A. Andreou, P. Vegh, S. Donovan, R. Fragkoudis, S. Panke, E. Wallace, A. Elfick, L. Rios-Solis. Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiaeand Emerging Yeast Species. 2022. ACS synthetic biology. 11, 527-547
- Malci, L. E. Walls and L Rios-Solis. Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments. 2022. ACS Synthetic Biology, 11, 4, 1555–1567
- Jonguitud-Borrego, K. Malcı, M. Anand, E. Baluku, C. Webb, L. Liang, C. Barba-Ostria, L. P Guaman, L. Hui, L. Rios-Solis. High—throughput and automated screening for COVID-19. 2022. Frontiers in Medical Technology. (4)
- H. Santoyo-Garcia, L. E. Walls, B. Nowrouzi, G.R Galindo-Rodriguez, M. Ochoa-Villareal, G. J. Loake, S. Dimartino, L.Rios-Solis. In situ solid-liquid extraction enhances recovery of taxadiene from engineered S. cerevisiae cell factories. 2022. Journal of Separation and Purification Sciences, 290, 120880
- Thangsunan, S. Temisak, T. Jaimalai, L Rios-Solis, N Suree. Sensitive Detection of Chicken Meat in Commercial Processed Food Products Based on One-Step Colourimetric Loop-Mediated Isothermal Amplification. 2022. Food Analytical Methods, 1-15
- E Walls, J.L Martinez, E.A del Rio Chanona, L Rios‐Solis. Definitive screening accelerates Taxol biosynthetic pathway optimization and scale up in Saccharomyces cerevisiaecell factories 2022. Biotechnology Journal, 17 (1), 210041
- E. Walls, J. L. Martinez, L. Rios-Solis. Enhancing Saccharomyces cerevisiaeTaxane Biosynthesis and Overcoming Nutritional Stress-Induced Pseudohyphal Growth. 2022. Microorganisms.10(1):163
2021
- P. Guaman-Bautista, E. Moreta U, C. G. O.-Arias, M. Torres-Arias, N. C. Kyriakidis, K. Malcı, N.Jonguitud-Borrego, L. Rios-Solis, E. Ramos-Martinez, A. López-Cortés, C. Barba-Ostria. Tracking SARS-Cov-2: Novel Trends and Diagnostics Strategies. 2021. Journal of Diagnostics . 11, 1981.
- Morris, R. Gacia Arrazola, L. Rios-Solis and P. A. Dalby. Biophysical characterization of E.Coli transketolase by aqueous cosolvents. 2021.Nature Scientific Report .11,1, 1-16.
- Teworte, K. Malcı, L. E. Walls, M. Halim, L. Rios-Solis Recent advances in fed-batch microscale bioreactor design. 2021. Biotechnology Advances. 107888
- Temisak, J. Boonil, W. Yenchum, K. Hongthong, T. yat, L. Rios-Solis and P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration 2021. International Journal of Food Science and Technology. 56,12, 6345-6358
- Nowrouzi, L. Rios-Solis. Redox metabolism for improving whole-cell P450-catalysed terpenoid biosynthesis 8 november 2021. Critical Reviews in Biotechnology. 1-25
- Muhammad Fakhri Zainuddin, Chong Kar Fai, Arbakariya B Ariff, Leonardo Rios-Solis, Murni Halim. Current Pretreatment/Cell Disruption and Extraction Methods Used to Improve Intracellular Lipid Recovery from Oleaginous Yeasts. 2021. Microorganisms 9(2), 251
2020
L. Walls, K. Malci, B. Nowrouzi, R. Li, L. d’Espaux, J. Wong, J. Dennis, A. Semiao, S. Wallace, J. Martinez, J. D. Keasling, L. Rios-Solis. Optimising the biosynthesis of oxygenated and acetylated Taxol precursors in S. cerevisiae using advanced bioprocessing strategies. Biotech BioEng J. 2020. https://doi.org/10.1002/bit.27569
B. Nowrouzi, R. Li, L. E. Walls, L. d’Espaux, K. Malci, L. Liang, N. Jonguitud Borrego, A. I. Lerma Escalera, J. R. Morones-Ramirez, J. D. Keasling, L. Rios Solis. Enhanced production of taxadiene in S. cerevisiae. Manuscript accepted for publication at Microb. Cell Fac. 2020. doi.org/10.1101/2020.06.08.13960
K. Malci, L E. Walls. L. Rios-Solis. Multiplex Genome Engineering Methods for Yeast Cell Factory Development. Epub ahead of publication. Front. Bioeng. Biotechnol. 2020. doi: 10.3389/fbioe.2020.589468
P. Morris, R. Garcia Arrazola, L. Rios-Solis, Paul A Dalby. Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents. BioRxiv. 2020. doi.org/10.1101/2020.06.09.140988
P. Thangsunan, S. Temisak, P. Morris, L. Rios-Solis, N. Suree. Combination of loop-mediated isothermal amplification and AuNP-oligoprobe colourimetric assay for pork authentication in processed-meat products. Paper accepted for publication at J. Food Anal. Methods. 2020. doi.org/10.1101/2020.07.12.199091
S. Temisak, P. Thangsunan, J. Boonil, W. Yenchum, K. Hongthong, T. Yata, L. Rios-Solis, P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration. BioRxiv 2020. doi.org/10.1101/2020.06.14.150375
L. E. Walls, L. Rios-Solis. Sustainable microbial isoprenoid derived advanced biojet fuel production: a review. J. Biotech. Bioeng. Epub ahead of publication. 2020. doi:10.3389/fbioe.2020.599560
J. Beal, A. Go.i‐Moreno, C. Myers, A. Hecht, M. del Carmen de Vicente, M. Parco, M. Schmidt, K. Timmis, G. Baldwin, S. Friedrichs, P. Freemont, D. Kiga, E. Ordozgoiti, M. Rennig, L. Rios Solis, K. Tanner, V. de Lorenzo, M. Porcar. The long journey towards standards for engineering biosystems. EMBO Rep. 2020. 6; 21(5). doi.org/10.15252/embr.202050521
2018
P. Wilk, H. Murni, L. Rios-Solis. 2018. Recent Advances and Impacts of Microtiter Plate-Based Fermentations in Synthetic Biology and Bioprocess Development. Fermentation Microbiology and Biotechnology, 4th edition. Taylor and Francis Publishers. 18:359-372
N.F Fazilah, A.B Ariff, M.E Khayat, L. Rios-Solis, M Halim. 2018. Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt. J. Funct. Foods 48, 387-399. doi.org/10.1016/j.jff.2018.07.039
M. Othman, A. B. Ariff, M. R. Kapri, L. Rios-Solis, M. Halim. 2018. Growth enhancement of probiotic Pediococcus acidilactici by extractive fermentation of lactic acid exploiting anion-exchange resin. Fronts. Microbiol. 9, 2554. doi.org/10.3389/fmicb.2018.02554
J. Wong, T. de Rond, L. d’Espaux, C. V. Horst, I. Dev, L. Rios-Solis, J. Kirby, H. Scheller, Jay Keasling. 2018. High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae. Metab. Eng. 45:142-148. doi.org/10.1016/j.ymben.2017.12.007
2017
M. Othman, A. B. Ariff, L. Rios-Solis, M. Halim. 2017. Extractive Fermentation of Lactic Acid in Lactic Acid Bacteria Cultivation: A Review. Fronts. Microbiol. 8: 2285 doi.org/10.3389/fmicb.2017.02285
J. Wong, L. Rios-Solis, J. D. Keasling. Microbial production of isoprenoids. 2017. Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals. Part of the series Handbook of Hydrocarbon and Lipid Microbiology Springer, Berlin, Germany pp. 21-24.
K. Markošov., I. Dolejš, R. Stloukal, L. Rios-Solis, M. Rosenberg, M. Micheletti, G. J. Lye, N. J. Turner, M. Rebroš. 2016. Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels. J. Mol. Cat. B. Enz. 129:69-74. doi.org/10.1016/j.molcatb.2016.04.009
2016
P. Morris, L. Rios-Solis, R. Garc.a-Arrazola, G. J. Lye and P. A. Dalby. 2016. Impact of cofactorbinding loop mutations on thermotolerance and activity of E. coli transketolase. Enz Microb Tech. 89:85-91. DOI: 10.1016/j.enzmictec.2016.04.003
L. Rios-Solis, P. Morris, H. Al-Bahrani, C. Du. Immobilized biospheres filtration system using unidirectional flow. U.K. Patent Application GB1602673.4, filed 16 February 2016. Patent Pending.
2015
L. Rios-Solis, B. Mothia, S. Yi, Z.Yuhong, M. Micheletti and G. J. Lye. 2015. High throughout monoamine oxidase (MAO-N) screening and kinetic model generation. J. Mol. Cat. B. Enz. 120-100-110. doi.org/10.1016/j.molcatb.2015.07.001
L. Rios-Solis, P. Morris, A. Odeleye, C. Grant, J.M. Ward, P.A. Dalby, F. Baganz and G.J. Lye. 2015. Modelling and optimization of the one-pot synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. Chem. Eng Sci. 122: 360–372. DOI:10.1016/J.CES.2014.09.046
2014
C.J. Du, L. Rios-Solis, J.M. Ward, P. A. Dalby, G. J. Lye. 2014. Evaluation of the CV2025 ω-transaminase for the bioconversion of lignin breakdown products into value-added chemicals. Biocat. Biotrans. 32:302-313. doi.org/10.3109/10242422.2014.976632
M. Halim, L. Rios-Solis. M. Micheletti, J. M. Ward and G.J. Lye. 2014. Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines. Bioprocess Biosyst. Eng. 37:931-41. DOI: 10.1007/s00449-013-1065-5
2013
L. Rios-Solis, N. Bayir, M. Halim., J. Hao, F. Baganz., G.J. Lye. 2013. Non-linear kinetic modelling of reversible bioconversions: application to the transaminase catalysed synthesis of chiral amino-alcohols. Biochem. Eng. J. 73:38-48. doi.org/10.1016/j.bej.2013.01.010
2011
L. Rios-Solis, M. Halim, A. C.zares, P. Morris, J. M. Ward, H.C. Hailes, P.A. Dalby, F. Baganz and G.J. Lye. 2011. A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’ E. coli expression system with microscale experimentation. Biocat. Biotrans. 29: 192-203. doi.org/10.3109/10242422.2011.609589
2010
A. C.zares, J. L. Galman, L. G. Crago, M. E. B. Smith, J. Strafford, L. Rios-Solis, G. J. Lye, P. A. Dalby and H. C. Hailes. 2010. Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes. Org. Biomol. Chem. 8: 1301–1309. DOI: 10.1039/b924144b
2009
F. Baganz, S. Matosevic, L. Rios, G. Lye, A. Jadhav, N. Szita. 2009. Towards engineering of de novo pathways for the synthesis of chiral chemicals using in vitro and in vivo approaches. New Biotechnol. 25: 159-160. 10.1016/j.nbt.2009.06.511
2023
- JH Santoyo‐Garcia, L. E Walls, M. Valdivia‐Cabrera, K. Malcı, N. Jonguitud‐Borrego, K. J Halliday, L. Rios‐Solis. The synergetic effect from the combination of different adsorption resins in batch and semi-continuous cultivations of S. cerevisiaecell factories to produce acetylated Taxanes precursors of the anticancer drug Taxol. 2023. Biotechnology and Bioengineering. 20 (2160-2174)
- J Vicencio-Medina, Y. A Rios-Solis, O. J. Ibarra-Rojas, N. M Cid-Garcia, L. Rios-Solis. The maximal covering location problem with accessibility indicators and mobile units. 2023. Socio-Economic Planning Sciences. 87 (101597)
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. R. Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2023. Critical Reviews in Biotechnology. (4) 594-612
- R Galindo-Rodriguez, J. H Santoyo-Garcia, L. Rios-Solis, S. Dimartino. In situ recovery of taxadiene using solid adsorption in cultivations with Saccharomyces cerevisiae. 2023. Preparative Biochemistry & Biotechnology. 1(9)
- Ripoll, J. Alexis Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis, L. Betancor. New perspectives into Gluconobacter-catalysed biotransformations. 2023. Biotechnology Advances 65 (108127)
- Imanina Abdullah Thaidi, R. Mohamad, H. Wasoh, M. Rizal Kapri, A. Badruddin Ghazali, J. Shun Tan, L. Rios-Solis, M. Halim. Development of In Situ Product Recovery (ISPR) System Using Amberlite IRA67 for Enhanced Biosynthesis of Hyaluronic Acid by Streptococcus zooepidemicus 2023. Life. 13-558
- Kerem Kalkan, F. Palaz, S. Sofija, N. Elmousa, Y. Ledezma, E. Cachat, L. Rios-Solis. Improving recombinant protein production in CHO cells using the CRISPR-Cas system. 2023. Biotechnology Advances. 64 (108115)
- Pannerchelvan, L. Rios-Solis, F. Wong Faizal Wong, U. Hasanah Zaidan, H. Wasoh, M. Shamzi Mohamed, J. Shun Tan, R. Mohamad, M. Halim. Strategies for improvement of gamma-aminobutyric acid (GABA) biosynthesis via lactic acid bacteria (LAB) fermentation. 2023. Food Funct , Advance Article
- Dwibedi, S. Kumar Rath, S. Jain, N. Martínez-Argueta, R. Prakash, S. Saxena, L. Rios-Solis. Key insights into secondary metabolites from various Chaetomium species. 2023, Applied Microbiology and Biotechnology. 107, 1077–1093
- M. El-Sharoud, S. A Zalma, L. Rios-Solis, R. Ledesma-Amaro. Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox. 2023. Biotechnology Notes. 4, 14-19
- E. Walls, P. Otoupal, R. Ledesma-Amaro, S. B. Velasquez-Orta, J. M. Gladden, L. Rios-Solis. Bioconversion of cellulose into isoprenoid bio-jet fuel candidates using rumen bacteria and non-conventional yeast. 2023. Bioresources and Biotechnology. 368, 128216
2022
- Malci. N. Jonguitud-Borrego, H. van der Straten Waillet, U. Puodžiu̅naitė, E. J. Johnston, S. J. Rosser, and L. Rios-Solis. ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time. 2022. ACS synthetic biology. 11, 3629–3643
- Nowrouzi, L. Lungang, L. Rios-Solis. Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae. 2022. Microbial Cell Factories. 21(1), 1-24
- Otun, A. Escrich, I. Achilonu, M. Rauwane, J. A. Lerma-Escalera, J. Rubén Morones-Ramírez, L. Rios-Solis. The future of cassava in the era of biotechnology in Southern Africa. 2022. Critical Reviews in Biotechnology, 1-19
- J. Torres-Sebastian, J. G. Colli-Mull, L. Escobedo-Sanchez, D. Martinez-Fong, L. Rios-Solis, M. E Gutierrez-Castillo, G. López-Jiménez, M. L Moreno-Rivera, L. R Tovar-Galvez, A. J Espadas-Alvarez. Methane, a renewable biofuel: from organic waste to bioenergy. 2022. Biofuels. 13 (7) 907-917
- Malcl, E. Watts, T. Michelle Roberts, J. Yam Auxillos, B. Nowrouzi, H. Oss Boll, C. Nascimento, A. Andreou, P. Vegh, S. Donovan, R. Fragkoudis, S. Panke, E. Wallace, A. Elfick, L. Rios-Solis. Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiaeand Emerging Yeast Species. 2022. ACS synthetic biology. 11, 527-547
- Malci, L. E. Walls and L Rios-Solis. Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments. 2022. ACS Synthetic Biology, 11, 4, 1555–1567
- Jonguitud-Borrego, K. Malcı, M. Anand, E. Baluku, C. Webb, L. Liang, C. Barba-Ostria, L. P Guaman, L. Hui, L. Rios-Solis. High—throughput and automated screening for COVID-19. 2022. Frontiers in Medical Technology. (4)
- H. Santoyo-Garcia, L. E. Walls, B. Nowrouzi, G.R Galindo-Rodriguez, M. Ochoa-Villareal, G. J. Loake, S. Dimartino, L.Rios-Solis. In situ solid-liquid extraction enhances recovery of taxadiene from engineered S. cerevisiae cell factories. 2022. Journal of Separation and Purification Sciences, 290, 120880
- Thangsunan, S. Temisak, T. Jaimalai, L Rios-Solis, N Suree. Sensitive Detection of Chicken Meat in Commercial Processed Food Products Based on One-Step Colourimetric Loop-Mediated Isothermal Amplification. 2022. Food Analytical Methods, 1-15
- E Walls, J.L Martinez, E.A del Rio Chanona, L Rios‐Solis. Definitive screening accelerates Taxol biosynthetic pathway optimization and scale up in Saccharomyces cerevisiaecell factories 2022. Biotechnology Journal, 17 (1), 210041
- E. Walls, J. L. Martinez, L. Rios-Solis. Enhancing Saccharomyces cerevisiaeTaxane Biosynthesis and Overcoming Nutritional Stress-Induced Pseudohyphal Growth. 2022. Microorganisms.10(1):163
2021
- P. Guaman-Bautista, E. Moreta U, C. G. O.-Arias, M. Torres-Arias, N. C. Kyriakidis, K. Malcı, N.Jonguitud-Borrego, L. Rios-Solis, E. Ramos-Martinez, A. López-Cortés, C. Barba-Ostria. Tracking SARS-Cov-2: Novel Trends and Diagnostics Strategies. 2021. Journal of Diagnostics . 11, 1981.
- Morris, R. Gacia Arrazola, L. Rios-Solis and P. A. Dalby. Biophysical characterization of E.Coli transketolase by aqueous cosolvents. 2021.Nature Scientific Report .11,1, 1-16.
- Teworte, K. Malcı, L. E. Walls, M. Halim, L. Rios-Solis Recent advances in fed-batch microscale bioreactor design. 2021. Biotechnology Advances. 107888
- Temisak, J. Boonil, W. Yenchum, K. Hongthong, T. yat, L. Rios-Solis and P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration 2021. International Journal of Food Science and Technology. 56,12, 6345-6358
- Nowrouzi, L. Rios-Solis. Redox metabolism for improving whole-cell P450-catalysed terpenoid biosynthesis 8 november 2021. Critical Reviews in Biotechnology. 1-25
- Muhammad Fakhri Zainuddin, Chong Kar Fai, Arbakariya B Ariff, Leonardo Rios-Solis, Murni Halim. Current Pretreatment/Cell Disruption and Extraction Methods Used to Improve Intracellular Lipid Recovery from Oleaginous Yeasts. 2021. Microorganisms 9(2), 251
2020
L. Walls, K. Malci, B. Nowrouzi, R. Li, L. d’Espaux, J. Wong, J. Dennis, A. Semiao, S. Wallace, J. Martinez, J. D. Keasling, L. Rios-Solis. Optimising the biosynthesis of oxygenated and acetylated Taxol precursors in S. cerevisiae using advanced bioprocessing strategies. Biotech BioEng J. 2020. https://doi.org/10.1002/bit.27569
B. Nowrouzi, R. Li, L. E. Walls, L. d’Espaux, K. Malci, L. Liang, N. Jonguitud Borrego, A. I. Lerma Escalera, J. R. Morones-Ramirez, J. D. Keasling, L. Rios Solis. Enhanced production of taxadiene in S. cerevisiae. Manuscript accepted for publication at Microb. Cell Fac. 2020. doi.org/10.1101/2020.06.08.13960
K. Malci, L E. Walls. L. Rios-Solis. Multiplex Genome Engineering Methods for Yeast Cell Factory Development. Epub ahead of publication. Front. Bioeng. Biotechnol. 2020. doi: 10.3389/fbioe.2020.589468
P. Morris, R. Garcia Arrazola, L. Rios-Solis, Paul A Dalby. Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents. BioRxiv. 2020. doi.org/10.1101/2020.06.09.140988
P. Thangsunan, S. Temisak, P. Morris, L. Rios-Solis, N. Suree. Combination of loop-mediated isothermal amplification and AuNP-oligoprobe colourimetric assay for pork authentication in processed-meat products. Paper accepted for publication at J. Food Anal. Methods. 2020. doi.org/10.1101/2020.07.12.199091
S. Temisak, P. Thangsunan, J. Boonil, W. Yenchum, K. Hongthong, T. Yata, L. Rios-Solis, P. Morris. Accurate determination of meat mass fractions using DNA measurements for quantifying meat adulteration. BioRxiv 2020. doi.org/10.1101/2020.06.14.150375
L. E. Walls, L. Rios-Solis. Sustainable microbial isoprenoid derived advanced biojet fuel production: a review. J. Biotech. Bioeng. Epub ahead of publication. 2020. doi:10.3389/fbioe.2020.599560
J. Beal, A. Go.i‐Moreno, C. Myers, A. Hecht, M. del Carmen de Vicente, M. Parco, M. Schmidt, K. Timmis, G. Baldwin, S. Friedrichs, P. Freemont, D. Kiga, E. Ordozgoiti, M. Rennig, L. Rios Solis, K. Tanner, V. de Lorenzo, M. Porcar. The long journey towards standards for engineering biosystems. EMBO Rep. 2020. 6; 21(5). doi.org/10.15252/embr.202050521
2018
P. Wilk, H. Murni, L. Rios-Solis. 2018. Recent Advances and Impacts of Microtiter Plate-Based Fermentations in Synthetic Biology and Bioprocess Development. Fermentation Microbiology and Biotechnology, 4th edition. Taylor and Francis Publishers. 18:359-372
N.F Fazilah, A.B Ariff, M.E Khayat, L. Rios-Solis, M Halim. 2018. Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt. J. Funct. Foods 48, 387-399. doi.org/10.1016/j.jff.2018.07.039
M. Othman, A. B. Ariff, M. R. Kapri, L. Rios-Solis, M. Halim. 2018. Growth enhancement of probiotic Pediococcus acidilactici by extractive fermentation of lactic acid exploiting anion-exchange resin. Fronts. Microbiol. 9, 2554. doi.org/10.3389/fmicb.2018.02554
J. Wong, T. de Rond, L. d’Espaux, C. V. Horst, I. Dev, L. Rios-Solis, J. Kirby, H. Scheller, Jay Keasling. 2018. High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae. Metab. Eng. 45:142-148. doi.org/10.1016/j.ymben.2017.12.007
2017
M. Othman, A. B. Ariff, L. Rios-Solis, M. Halim. 2017. Extractive Fermentation of Lactic Acid in Lactic Acid Bacteria Cultivation: A Review. Fronts. Microbiol. 8: 2285 doi.org/10.3389/fmicb.2017.02285
J. Wong, L. Rios-Solis, J. D. Keasling. Microbial production of isoprenoids. 2017. Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals. Part of the series Handbook of Hydrocarbon and Lipid Microbiology Springer, Berlin, Germany pp. 21-24.
K. Markošov., I. Dolejš, R. Stloukal, L. Rios-Solis, M. Rosenberg, M. Micheletti, G. J. Lye, N. J. Turner, M. Rebroš. 2016. Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels. J. Mol. Cat. B. Enz. 129:69-74. doi.org/10.1016/j.molcatb.2016.04.009
2016
P. Morris, L. Rios-Solis, R. Garc.a-Arrazola, G. J. Lye and P. A. Dalby. 2016. Impact of cofactorbinding loop mutations on thermotolerance and activity of E. coli transketolase. Enz Microb Tech. 89:85-91. DOI: 10.1016/j.enzmictec.2016.04.003
L. Rios-Solis, P. Morris, H. Al-Bahrani, C. Du. Immobilized biospheres filtration system using unidirectional flow. U.K. Patent Application GB1602673.4, filed 16 February 2016. Patent Pending.
2015
L. Rios-Solis, B. Mothia, S. Yi, Z.Yuhong, M. Micheletti and G. J. Lye. 2015. High throughout monoamine oxidase (MAO-N) screening and kinetic model generation. J. Mol. Cat. B. Enz. 120-100-110. doi.org/10.1016/j.molcatb.2015.07.001
L. Rios-Solis, P. Morris, A. Odeleye, C. Grant, J.M. Ward, P.A. Dalby, F. Baganz and G.J. Lye. 2015. Modelling and optimization of the one-pot synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. Chem. Eng Sci. 122: 360–372. DOI:10.1016/J.CES.2014.09.046
2014
C.J. Du, L. Rios-Solis, J.M. Ward, P. A. Dalby, G. J. Lye. 2014. Evaluation of the CV2025 ω-transaminase for the bioconversion of lignin breakdown products into value-added chemicals. Biocat. Biotrans. 32:302-313. doi.org/10.3109/10242422.2014.976632
M. Halim, L. Rios-Solis. M. Micheletti, J. M. Ward and G.J. Lye. 2014. Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines. Bioprocess Biosyst. Eng. 37:931-41. DOI: 10.1007/s00449-013-1065-5
2013
L. Rios-Solis, N. Bayir, M. Halim., J. Hao, F. Baganz., G.J. Lye. 2013. Non-linear kinetic modelling of reversible bioconversions: application to the transaminase catalysed synthesis of chiral amino-alcohols. Biochem. Eng. J. 73:38-48. doi.org/10.1016/j.bej.2013.01.010
2011
L. Rios-Solis, M. Halim, A. C.zares, P. Morris, J. M. Ward, H.C. Hailes, P.A. Dalby, F. Baganz and G.J. Lye. 2011. A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a ‘mix and match’ E. coli expression system with microscale experimentation. Biocat. Biotrans. 29: 192-203. doi.org/10.3109/10242422.2011.609589
2010
A. C.zares, J. L. Galman, L. G. Crago, M. E. B. Smith, J. Strafford, L. Rios-Solis, G. J. Lye, P. A. Dalby and H. C. Hailes. 2010. Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes. Org. Biomol. Chem. 8: 1301–1309. DOI: 10.1039/b924144b
2009
F. Baganz, S. Matosevic, L. Rios, G. Lye, A. Jadhav, N. Szita. 2009. Towards engineering of de novo pathways for the synthesis of chiral chemicals using in vitro and in vivo approaches. New Biotechnol. 25: 159-160. 10.1016/j.nbt.2009.06.511