At LeoRios Lab, our research motivation focuses on promoting further understanding of the overlapping areas of Biochemical Engineering and Synthetic Biology, resulting in novel ways to apply this knowledge to tackle the global growing socio-economic inequalities. We have a firm belief that if scientists work together and gear their research and related activities towards this end, an immense contribution will be made fighting problems like equal access to food, energy and pharmaceuticals, boosting local bio-economies, access to high-quality education as well as the promotion of a sustainable environment. 

Our research areas
“What I cannot create, I do not understand”.- Richard Feynman

Microbiol Cell Factories: Synthetic Biology and Metabolic Engineering

Engineering Microbial Consortia

Engineering Microbial Consortia

Engineered Microbial Consortia In their natural habitat, microbial cells live in organised consortia reaching a steady state in terms of...

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CRISPR-Based Low-Cost Diagnostics

CRISPR-Based Low-Cost Diagnostics

We are working on developing and optimizing CRISPR-mediated nucleic acid detection methods for the detection of early-stage infections.

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Metabolic Engineering

Metabolic Engineering

Our group is working on applying synthetic biology tools to engineer microbial cell factories to produce high value a bulk products such as...

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Mammalian Cell Factories

Mammalian Cell Factories

Mammalian Cell Factories We are very excited to explore new production ways of biologics using mammalian cells. Therefore, we are venturing in...

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Multiplex Genome Engineering

Multiplex Genome Engineering

To accelerate strain development and heterologous pathway construction, we are developing multiple genome engineering methods by employing novel...

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Bioprocess Engineering

Integrated Bioprocessing

Integrated Bioprocessing

The configuration, composition and aims of the bioprocesses make them unique between each other, even if the target molecule and source of...

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Continuous Flow Bioprocessing

Continuous Flow Bioprocessing

The bioprocessing industry has been mainly studied and commercialized using batch and fed-batch production methods, while little focus has been...

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Bio-Automation

Open Source Automation with Artificial Intelligence for Synthetic Biology

Open Source Automation with Artificial Intelligence for Synthetic Biology

Open source automation augmented with AI is now being used by academia and industry.   Open source automation designs can be more affordable...

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High Throughput Microscale and Mini Bioreactors

High Throughput Microscale and Mini Bioreactors

  Microscale Automated Bioprocessing Tools Microscale bioreators and its further automation have been a critical tool for the development of...

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Digital microfluidics applied to Synthetic Biology

Digital microfluidics applied to Synthetic Biology

Our lab is using the digital microfluidics device which is developed by Digibio Company (DigiBio) to do yeast transformation using CRISPR/Cas9 in...

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Research Areas

We Develop Innovative Solutions

“Impossible only means you haven’t found the solution yet”. - Anonymous

Metabolic Engineering and Systems Biology

Microbial Cell Factories for the Sustainable Production of Drugs, Biomaterials and Biofuels

  • Anticancer Drug Taxol in S. cerevisiae
  • Jet Biofuels in Yarrowia Lipolytica
  • High Value Chiral Amino-alcohols in E. coli
  • High Value Alkaloids (i.e Ephedrine) in S. cerevisiae
  • Fragrances and Food Additives in E. coli and S. cerevisiae

High-throughput  Bioreactors

Mini and Microscale Bioreactors to Speed Up Bioprocess Development  Mimicking Large Scale Conditions

  • Advanced Microplate Based Bioreactors
  • Mini-Bioreactors Mimicking Industrial Scale Conditions
  • Microscale Continuous Flow Bioreactors
  • Low Cost 3D printed Bioreactors
  • Microfluidic MicroBioreactors

Smart Biosensors and Diagnostics

Synthetic Biology Tools Applied for Low-Cost Diagnostics and Biosensing Capabilities

  • CRISPR Based Diagnostics for COVID19
  • Biosensors Applied in Aquaculture
  • Digital Microfluidic Diagnostics

Automation and Artificial Intelligence

State of the Art Bio-Automation enhanced by Artificial Intelligence algorithms

  • Open Source Low Cost Automation
  • Edinburgh Genome BioFoundry
  • Bio-Automation Enhanced Through Artificial Intelligence
  • Automated Digital Microfluidics

Advanced Bioprocessing Technologies

Designing Novel Bioreactors and Intensified Bioprocesses to tackle Scale Up Challenges

  • Integrated Bioprocessing
  • Continuous Flow Bioprocesses
  • Scale up of Mammalian Cells Systems
  • Hybrid Biomodelling combining Machine Learning and deterministic algorithms
  • Life Cycle Assessments
Work With Us!

Opportunities

“If a window of opportunity appears, don’t pull down the shadow”. - Tom Peters
Postdoc and Fellowships Opportunities
Entrepreneurship
MSc, MScR and PhD Opportunities
Academic Partnerships
Industrial Collaborations
Visiting Students

About The Centre for Synthetic and Systems Biology (SynthSys)

Edinburgh’s Centre for Synthetic and Systems Biology (known as SynthSys) embraces a vibrant community of > 50 research groups and >200 researchers. Our research is broad and deep, addressing a diversity of scientific questions with wide ranging impacts for society, industry, the economy and our planet
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University Investment in Synbio and SysBio (£ million)
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Design, Buil and Measure World Class Core Facilities
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Researchers (PhDs, Postdocs, Technicians and Principal Investigators)
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Key Research Areas
Meet the Team

The Rising Stars of LeoRios Lab

``Coming together is a beginning. Keeping together is progress. Working together is success``. - Henry Ford
Nestor Jonguitud
Nestor Jonguitud
PhD Student: Microbial Consortia
Nestor came all the way from Tabasco, Mexico to pursue his PhD focusing on engineering microbial cells to work synergistically to produce natural...
Siddhant Sharma
Siddhant Sharma
Undergraduate Research Associate, Earth-Life Science Institute, Japan
Siddhant is an undergraduate research associate with Earth-Life Science Institute, Japan working in prebiotic chemistry and origins of life.
Behnaz Nowrouzi
Behnaz Nowrouzi
PhD Student: Metabolic Engineering
Behnaz has a keen interest on microbial-based natural product synthesis. She would like to introduce new insights into P450 enzymes research using...
Dr Leonardo Rios
Dr Leonardo Rios
Lecturer (Assistant Professor) of Synthetic Biology and Biochemical Engineering
Leonardo was awarded a lectureship in 2017 at the Engineering School of the University of Edinburgh where he leads his research group at the...
Koray Malci
Koray Malci
PhD Student: Metabolic Engineering, Automation and Diagnostics
Koray is focusing on microbial cell factory design using novel genome engineering tools and automation platforms to produce high-value...
Emma Watts
Emma Watts
BSc Hons Biotechnology
Emma is interested in the intersection of synthetic biology and sustainability.
from the blog

Learn About Our Latest News, Events, Leading Technologies and Research Outputs

BBQ in the Meadows!

BBQ in the Meadows!

On Sunday 30 of May, we got a nice weather and decided to organise our networking event in the meadows having a BBQ, colleagues from other groups of the School of...

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Group meeting outdoors at the Royal Dick

Group meeting outdoors at the Royal Dick

After missing out for almost a year without outdoor social meetings, the members of LeoRiosgroup had the change to organise a meeting at the Summerhall Royal Dick to...

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Digital Microfluidics Workship

Digital Microfluidics Workship

About the Biomedical Automation Network: The Biomedical Lab Automation (BLA) network aims to coordinate and maximize the potential of the University’s automation...

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testimonials

What People Say About Us

I did a period of research abroad at Leo Ríos’ lab. The whole group made me feel like I was at home during the time I was there and they really valued me as a member of the team. They shared their knowledge in the best way posible and I had responsibilities from day one. Leo is not only a great scientist, he is an amazing leader.

 

 

Gabriela Mellado (visiting student)
Gabriela MelladoVisiting Student
Glad to be a member of Dr. Leo’s lab. I have learned a lot in such a harmonious
atmosphere. Hope to keep updated on the well-designed website!
Junlin Dong (MSc Student)
Junlin DongMsc Student (Currently Research assistant in SIAT)

I’m really glad to have joined  Leo’s lab during my master year to conduct research on advanced machine scheduling for COVID-19 diagnosis optimization. I’m extremely impressed with the best scientific research atmosphere, the strongest scientific prowess, and the most harmonious relationships in this lab. These really helped me to make progress in my academic years and will benefit me in the future.

Yimeng Han (MSc Student)
Yimeng HanMsc Student
Contact Us

We are open for collaborations

“Individually, we are one drop. Together, we are an ocean”. - Ryunosuke Satoro
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