Our research areas
“What I cannot create, I do not understand”.- Richard Feynman

Microbiol Cell Factories: Synthetic Biology and Metabolic Engineering

Engineering Microbial Consortia

Engineering Microbial Consortia

Engineered Microbial Consortia In their natural habitat, microbial cells live in organised consortia reaching a steady state in terms of...

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CRISPR Based Low Cost Diagnostics

CRISPR Based Low Cost Diagnostics

The active agent of a vaccine may be intact but inactivated or attenuated (with reduced infectivity) forms of the causative pathogens.

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Metabolic Engineering

Metabolic Engineering

Our group is working on applying synthetic biology tools to engineer microbial cell factories to produce high value a bulk products such as...

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Mammalian Cell Factories

Mammalian Cell Factories

Mammalian Cell Factories We are very excited to explore new production ways of biologics using mammalian cells. Therefore, we are venturing in...

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Multiplex Genome Engineering

Multiplex Genome Engineering

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Bioprocess Engineering

Biocatalysis and Protein Engineering

Biocatalysis and Protein Engineering

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Integrated Bioprocessing

Integrated Bioprocessing

Synthetic biology has allowed the engineering of novel synthetic multi-enzymatic pathways to produce high value products in a sustainable way...

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Continuous Flow Bioprocessing

Continuous Flow Bioprocessing

The bioprocessing industry has been mainly studied and commercialized using batch and fed-batch production methods, while little focus has been...

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Hybrid Biomodelling: Deterministic and Machine Learning Algorithms

Hybrid Biomodelling: Deterministic and Machine Learning Algorithms

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Bio-Automation

Open Source Bio-automation

Open Source Bio-automation

A drug that legally requires a medical prescription to be dispensed. Over-the-counter drugs can be obtained without a prescription.

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High Throughput Microscale and Mini Bioreactors

High Throughput Microscale and Mini Bioreactors

  Microscale Automated Bioprocessing Tools Microscale bioreators and its further automation have been a critical tool for the development of...

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Digital Bio-microfluidics

Digital Bio-microfluidics

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Research Areas

We Develop Innovative Solutions

“Impossible only means you haven’t found the solution yet”. - Anonymous

Metabolic Engineering and Systems Biology

Microbial Cell Factories for the Sustainable Production of Drugs, Biomaterials and Biofuels

  • Anticancer Drug Taxol in S. cerevisiae
  • Jet Biofuels in Yarrowia Lipolytica
  • High Value Chiral Amino-alcohols in E. coli
  • High Value Alkaloids (i.e Ephedrine) in S. cerevisiae
  • Fragrances and Food Additives in E. coli and S. cerevisiae

High-throughput  Bioreactors

Mini and Microscale Bioreactors to Speed Up Bioprocess Development  Mimicking Large Scale Conditions

  • Advanced Microplate Based Bioreactors
  • Mini-Bioreactors Mimicking Industrial Scale Conditions
  • Microscale Continuous Flow Bioreactors
  • Low Cost 3D printed Bioreactors
  • Microfluidic MicroBioreactors

Smart Biosensors and Diagnostics

Synthetic Biology Tools Applied for Low-Cost Diagnostics and Biosensing Capabilities

  • CRISPR Based Diagnostics for COVID19
  • Biosensors Applied in Aquaculture
  • Digital Microfluidic Diagnostics

Automation and Artificial Intelligence

State of the Art Bio-Automation enhanced by Artificial Intelligence algorithms

  • Open Source Low Cost Automation
  • Edinburgh Genome BioFoundry
  • Bio-Automation Enhanced Through Artificial Intelligence
  • Automated Digital Microfluidics

Advanced Bioprocessing Technologies

Designing Novel Bioreactors and Intensified Bioprocesses to tackle Scale Up Challenges

  • Integrated Bioprocessing
  • Continuous Flow Bioprocesses
  • Scale up of Mammalian Cells Systems
  • Hybrid Biomodelling combining Machine Learning and deterministic algorithms
  • Life Cycle Assessments
Work With Us!

Opportunities

“If a window of opportunity appears, don’t pull down the shadow”. - Tom Peters
Postdoc and Fellowships Opportunities
Entrepreneurship
MSc, MScR and PhD Opportunities
Academic Partnerships
Industrial Collaborations
Visiting Students

About The Centre for Synthetic and Systems Biology (SynthSys)

Edinburgh’s Centre for Synthetic and Systems Biology (known as SynthSys) embraces a vibrant community of > 50 research groups and >200 researchers. Our research is broad and deep, addressing a diversity of scientific questions with wide ranging impacts for society, industry, the economy and our planet
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University Investment in Synbio and SysBio (£ million)
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Design, Buil and Measure World Class Core Facilities
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Researchers (PhDs, Postdocs, Technicians and Principal Investigators)
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Key Research Areas
Meet the Team

The Rising Stars of LeoRios Lab

``Coming together is a beginning. Keeping together is progress. Working together is success``. - Henry Ford
Laura E. Walls
Laura E. Walls
PhD Student: Bioprocess Engineering
Laura focuses on the development of an industrially relevant, scalable bioprocess for the production of high value isoprenoids. Laura is using...
Behnaz Nowrouzi
Behnaz Nowrouzi
PhD Student: Metabolic Engineering
Behnaz is focusing on genome engineering using plants P450 in yeast. These enzymes are promiscuous and therefore, minimizing by-products, while...
Nestor Jonguitud
Nestor Jonguitud
PhD Student: Microbial Consortiums
Nestor came all the way from Tabasco, Mexico to pursue his PhD focusing on engineering microbial cells to work synergistically to produce natural...
Jorge Santoyo
Jorge Santoyo
PhD Student: Integrated Bioprocessing
Integrated Bioprocess design, developing novel high throughput recovery methods of high value natural products from cell factories using novel...
Koray Malci
Koray Malci
PhD Student: Metabolic Engineering, Automation and Diagnostics
Koray is focusing on microbial cell factory design using novel genome engineering tools and automation platforms to produce high value...
from the blog

Learn About Our Leading Technologies

Novel Technologies…

Novel Technologies…

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Targeting Cancer…

Targeting Cancer…

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Antibody Development…

Antibody Development…

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Contact Us

We are open for collaborations

“Individually, we are one drop. Together, we are an ocean”. - Ryunosuke Satoro
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